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Chemical structure of CMC2·24

GC62347

CMC2·24

Also known as (E)-5-(4-hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide

CMC2·24 (TRB-N0224), an orally active tricarbonylmethane agent, is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway

ChemicalCAS1255639-43-0MW427.45FormulaC26H21NO5
CAS number
1255639-43-0
Molecular weight
427.45
Formula
C26H21NO5
Solubility
DMSO ： ＜ 1 mg/mL (insoluble or slightly soluble)
InChIKey
ZPZMHBPRQOJARQ-OTYYAQKOSA-N
Catalogue number
GC62347
Brand
GLPBIO
Computed properties PubChem CID 49806131 · XLogP 4.9 · TPSA 104 Ų · H-bond donors 3
XLogP
4.9
TPSA
104 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
32

SMILES C1=CC=C(C=C1)NC(=O)C(C(=O)/C=C/C2=CC=C(C=C2)O)C(=O)/C=C/C3=CC=C(C=C3)O

Computed descriptors from PubChem (CID 49806131), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.