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Chemical structure of Rezivertinib

GC62341

Rezivertinib

Also known as N-[2-[2-(dimethylamino)ethoxy]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide

Rezivertinib (BPI-7711) is an orally active, highly selective and irreversible third-generation EGFR tyrosine kinase inhibitor (TKI)· Rezivertinib exhibits high potency against the common activation EGFR and the resistance T790M mutations· Rezivertinib has excellent central nervous system (CNS) penetration and has antitumor activity

ChemicalCAS1835667-12-3MW486.57FormulaC27H30N6O3
CAS number
1835667-12-3
Molecular weight
486.57
Formula
C27H30N6O3
Solubility
DMSO ： 125 mg/mL (256·90 mM; Need ultrasonic)
InChIKey
BPMZUKYFIDPLEA-UHFFFAOYSA-N
Catalogue number
GC62341
Brand
GLPBIO
Computed properties PubChem CID 118912975 · XLogP 3.6 · TPSA 93.5 Ų · H-bond donors 2
XLogP
3.6
TPSA
93.5 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
36

SMILES CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=CC(=C(C=C4OC)OCCN(C)C)NC(=O)C=C

Computed descriptors from PubChem (CID 118912975), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.