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Chemical structure of mTOR inhibitor-8

GC62339

mTOR inhibitor-8

Also known as 2-[5-(4-chlorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]-4-pyridin-4-yl-1,3-thiazole

mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer· mTOR inhibitor-8 inhibits the activity of mTOR via FKBP12 and induces autophagy of A549 human lung cancer cells

ChemicalCAS2489196-70-3MW446.95FormulaC24H19ClN4OS
CAS number
2489196-70-3
Molecular weight
446.95
Formula
C24H19ClN4OS
Solubility
DMSO ： 25 mg/mL (55·93 mM; Need ultrasonic)
InChIKey
YYORGGAMBAZQIJ-UHFFFAOYSA-N
Catalogue number
GC62339
Brand
GLPBIO
Computed properties PubChem CID 154573769 · XLogP 5.6 · TPSA 78.9 Ų · H-bond donors 0
XLogP
5.6
TPSA
78.9 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
31

SMILES COC1=CC=C(C=C1)C2CC(=NN2C3=NC(=CS3)C4=CC=NC=C4)C5=CC=C(C=C5)Cl

Computed descriptors from PubChem (CID 154573769), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.