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Chemical structure of DBCO-Maleimide

GC62325

DBCO-Maleimide

Also known as N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide

DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS1395786-30-7MW427.45FormulaC25H21N3O4
CAS number
1395786-30-7
Molecular weight
427.45
Formula
C25H21N3O4
Solubility
DMSO : 125 mg/mL (292·43 mM; ultrasonic and warming and heat to 60°C)
InChIKey
NHFQNAGPXIVKND-UHFFFAOYSA-N
Catalogue number
GC62325
Brand
GLPBIO
Computed properties PubChem CID 77078149 · XLogP 1.3 · TPSA 86.8 Ų · H-bond donors 1
XLogP
1.3
TPSA
86.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
32

SMILES C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCN4C(=O)C=CC4=O

Computed descriptors from PubChem (CID 77078149), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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