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Chemical structure of GRL-0496

GC62221

GRL-0496

Also known as (5-chloro-3-pyridinyl) 1H-indole-4-carboxylate

GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays

ChemicalCAS1087243-14-8MW272.69FormulaC14H9ClN2O2
CAS number
1087243-14-8
Molecular weight
272.69
Formula
C14H9ClN2O2
InChIKey
BOSZJNSICHFHMA-UHFFFAOYSA-N
Catalogue number
GC62221
Brand
GLPBIO
Computed properties PubChem CID 25110701 · XLogP 2.8 · TPSA 55 Ų · H-bond donors 1
XLogP
2.8
TPSA
55 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
19

SMILES C1=CC(=C2C=CNC2=C1)C(=O)OC3=CC(=CN=C3)Cl

Computed descriptors from PubChem (CID 25110701), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.