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Chemical structure of Dxd-D5

GC62212

Dxd-D5

Dxd-d5 (Exatecan-d5 derivative for ADC) is a deuterium labeled Dxd· Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0·31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a)

ChemicalMW498.51FormulaC26H19D5FN3O6
CAS number
—
Molecular weight
498.51
Formula
C26H19D5FN3O6
Solubility
DMSO ： 100 mg/mL (200·60 mM; ultrasonic and warming and heat to 60°C)
Catalogue number
GC62212
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.