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Chemical structure of Thalidomide-NH-PEG4-COOH

GC62204

Thalidomide-NH-PEG4-COOH

Also known as 3-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1· dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP

ChemicalCAS2412056-48-3MW521.52FormulaC24H31N3O10
CAS number
2412056-48-3
Molecular weight
521.52
Formula
C24H31N3O10
Solubility
DMSO : 80 mg/mL (153·40 mM; Need ultrasonic)
InChIKey
LKZFZWXIYMGKMH-UHFFFAOYSA-N
Catalogue number
GC62204
Brand
GLPBIO
Computed properties PubChem CID 146410751 · XLogP -0.8 · TPSA 170 Ų · H-bond donors 3
XLogP
-0.8
TPSA
170 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
17
Heavy atoms
37

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)NCCOCCOCCOCCOCCC(=O)O

Computed descriptors from PubChem (CID 146410751), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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