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Chemical structure of (1S,2S)-Bortezomib

GC62193

(1S,2S)-Bortezomib

Also known as [(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid

(1S,2S)-Bortezomib is an enantiomer of Bortezomib· Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0·6 nM) by targeting a threonine residue· Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB· Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans

ChemicalCAS1132709-14-8MW384.24FormulaC19H25BN4O4
CAS number
1132709-14-8
Molecular weight
384.24
Formula
C19H25BN4O4
Solubility
DMSO ： 50 mg/mL (130·13 mM; Need ultrasonic)
InChIKey
GXJABQQUPOEUTA-DOTOQJQBSA-N
Catalogue number
GC62193
Brand
GLPBIO
Computed properties PubChem CID 24871309 · TPSA 124 Ų · H-bond donors 4 · H-bond acceptors 6
TPSA
124 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
28

SMILES B([C@@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

Computed descriptors from PubChem (CID 24871309), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.