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Chemical structure of CP5V

GC62181

CP5V

Also known as 3-[3-[2-[2-[2-[2-[3-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]propyl N-[2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate

CP5V is a PROTAC connected by ligands for von Hippel-Lindau and CDK, which specifically degrades Cdc20 by linking Cdc20 to the VHL/VBC complex for ubiquitination followed by proteasomal degradation· CP5V induces mitotic inhibition and suppresses cancer cell proliferation

ChemicalCAS2509359-75-3MW1075.49FormulaC46H66Cl3N9O12S
CAS number
2509359-75-3
Molecular weight
1075.49
Formula
C46H66Cl3N9O12S
Solubility
DMSO ： 150 mg/mL (139·47 mM; Need ultrasonic)
InChIKey
BQQILUVLGKHSNJ-NWRQRLFSSA-N
Catalogue number
GC62181
Brand
GLPBIO
Computed properties PubChem CID 139600343 · XLogP 3.7 · TPSA 291 Ų · H-bond donors 6
XLogP
3.7
TPSA
291 Ų
H-bond donors
6
H-bond acceptors
17
Rotatable bonds
33
Heavy atoms
71

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCOCCOCCOCCOCCOCCC(=O)NCCCOC(=O)NC(C(Cl)(Cl)Cl)NC4=NC=CC=N4)O

Computed descriptors from PubChem (CID 139600343), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.