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Chemical structure of Fluorizoline

GC62167

Fluorizoline

Also known as 2,5-bis(4-chlorophenyl)-4,4,5-trifluoro-1,3-thiazole

Fluorizoline selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2), and induces apoptosis· Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM· Fluorizoline exerts antitumor action in a p53-independent manner

ChemicalCAS1362243-70-6MW362.2FormulaC15H8Cl2F3NS
CAS number
1362243-70-6
Molecular weight
362.2
Formula
C15H8Cl2F3NS
Solubility
DMSO ： 50 mg/mL (138·05 mM; Need ultrasonic)
InChIKey
JGDLZQYCDVDWNE-UHFFFAOYSA-N
Catalogue number
GC62167
Brand
GLPBIO
Computed properties PubChem CID 56837157 · XLogP 5.8 · TPSA 37.7 Ų · H-bond donors 0
XLogP
5.8
TPSA
37.7 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
22

SMILES C1=CC(=CC=C1C2=NC(C(S2)(C3=CC=C(C=C3)Cl)F)(F)F)Cl

Computed descriptors from PubChem (CID 56837157), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.