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Chemical structure of UT-34

GC62124

UT-34

Also known as (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluoropyrazol-1-yl)-2-hydroxy-2-methylpropanamide

UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211·7 nM, 262·4 nM and 215·7 nM for wild-type, F876L and W741L AR, respectively

ChemicalCAS2168525-92-4MW356.27FormulaC15H12F4N4O2
CAS number
2168525-92-4
Molecular weight
356.27
Formula
C15H12F4N4O2
Solubility
DMSO ： 250 mg/mL (701·71 mM; Need ultrasonic)
InChIKey
YDRMSDHDYRAUBR-AWEZNQCLSA-N
Catalogue number
GC62124
Brand
GLPBIO
Computed properties PubChem CID 132214622 · XLogP 1.3 · TPSA 90.9 Ų · H-bond donors 2
XLogP
1.3
TPSA
90.9 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
25

SMILES C[C@](CN1C=C(C=N1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O

Computed descriptors from PubChem (CID 132214622), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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