GC62111
PND-1186 hydrochloride
Also known as 2-[[2-(2-methoxy-4-morpholin-4-ylanilino)-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide;hydrochloride
PND-1186 hydrochloride (VS-4718 hydrochloride) is a potent, highly-specific and reversible inhibitor of FAK with an IC50 of 1·5 nM· PND-1186 hydrochloride selectively promotes tumor cell apoptosis
ChemicalCAS1356154-94-3MW537.96FormulaC25H27ClF3N5O3
- CAS number
- 1356154-94-3
- Molecular weight
- 537.96
- Formula
- C25H27ClF3N5O3
- Solubility
- DMSO ： 200 mg/mL (371·77 mM; Need ultrasonic)|Water ： 20 mg/mL (37·18 mM; Need ultrasonic)
- InChIKey
- OWQFAUOQRRIFLB-UHFFFAOYSA-N
- Catalogue number
- GC62111
- Brand
- GLPBIO
Computed properties PubChem CID 56654067 · TPSA 87.8 Ų · H-bond donors 4 · H-bond acceptors 10
- TPSA
- 87.8 Ų
- H-bond donors
- 4
- H-bond acceptors
- 10
- Rotatable bonds
- 7
- Heavy atoms
- 37
SMILES CNC(=O)C1=CC=CC=C1NC2=CC(=NC=C2C(F)(F)F)NC3=C(C=C(C=C3)N4CCOCC4)OC.Cl
Computed descriptors from PubChem (CID 56654067), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il