Loading...
Chemical structure of Manzamine A hydrochloride

GC62015

Manzamine A hydrochloride

Also known as (1R,2R,4R,5Z,12R,13S,16Z)-25-(9H-pyrido[3,4-b]indol-1-yl)-22-aza-11-azoniapentacyclo[11.11.2.12,22.02,12.04,11]heptacosa-5,16,25-trien-13-ol chloride

Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10·2 μM and 1·5 μM, respectively

ChemicalCAS104264-80-4MW585.22FormulaC36H45ClN4O
CAS number
104264-80-4
Molecular weight
585.22
Formula
C36H45ClN4O
Solubility
DMSO ： 5·88 mg/mL (10·05 mM; Need ultrasonic)
InChIKey
DIVWQABXFSWTEF-YTGAITGWSA-N
Catalogue number
GC62015
Brand
GLPBIO
Computed properties PubChem CID 9894648 · TPSA 56.6 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
56.6 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
1
Heavy atoms
42

SMILES C1CC[NH+]2[C@H](C[C@]34[C@@H]2[C@@]5(CC/C=C\CCCCN(C3)CC[C@H]4C(=C5)C6=NC=CC7=C6NC8=CC=CC=C78)O)/C=C\C1.[Cl-]

Computed descriptors from PubChem (CID 9894648), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.