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Chemical structure of Cl-NQTrp

GC61887

Cl-NQTrp

Also known as (2S)-2-[(3-chloro-1,4-dioxonaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid

Cl-NQTrp signifcantly disrupts the preformed fbrillar aggregates of Tau-derived PHF6 (VQIVYK) peptide and full-length tau protein

ChemicalCAS185351-23-9MW394.81FormulaC21H15ClN2O4
CAS number
185351-23-9
Molecular weight
394.81
Formula
C21H15ClN2O4
Solubility
DMSO : 250 mg/mL (633·22 mM; Need ultrasonic)
InChIKey
ZKNQSBBALRSDBQ-INIZCTEOSA-N
Catalogue number
GC61887
Brand
GLPBIO
Computed properties PubChem CID 1427125 · XLogP 4.2 · TPSA 99.3 Ų · H-bond donors 3
XLogP
4.2
TPSA
99.3 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
28

SMILES C1=CC=C2C(=C1)C(=O)C(=C(C2=O)Cl)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O

Computed descriptors from PubChem (CID 1427125), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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