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Chemical structure of DBCO-C6-acid

GC61874

DBCO-C6-acid

Also known as 6-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-6-oxohexanoic acid

DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· DBCO-C6-acid can be used in the synthesis of carmaphycin analogues

ChemicalCAS1425485-72-8MW333.38FormulaC21H19NO3
CAS number
1425485-72-8
Molecular weight
333.38
Formula
C21H19NO3
Solubility
DMSO : 100 mg/mL (299·96 mM)
InChIKey
NIRLBCOFKPVQLM-UHFFFAOYSA-N
Catalogue number
GC61874
Brand
GLPBIO
Computed properties PubChem CID 77078156 · XLogP 3 · TPSA 57.6 Ų · H-bond donors 1
XLogP
3
TPSA
57.6 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
25

SMILES C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCCCC(=O)O

Computed descriptors from PubChem (CID 77078156), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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