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Chemical structure of Azido-PEG6-NHS ester

GC61869

Azido-PEG6-NHS ester

Also known as (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS2055014-64-5MW476.48FormulaC19H32N4O10
CAS number
2055014-64-5
Molecular weight
476.48
Formula
C19H32N4O10
Solubility
DMSO : 100 mg/mL (209·87 mM)
InChIKey
WXKOAPGNZNSYPW-UHFFFAOYSA-N
Catalogue number
GC61869
Brand
GLPBIO
Computed properties PubChem CID 77078479 · XLogP -0.8 · TPSA 133 Ų · H-bond donors 0
XLogP
-0.8
TPSA
133 Ų
H-bond donors
0
H-bond acceptors
12
Rotatable bonds
23
Heavy atoms
33

SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Computed descriptors from PubChem (CID 77078479), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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