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Chemical structure of Mofezolac

GC61843

Mofezolac

Also known as 2-[3,4-bis(4-methoxyphenyl)-1,2-oxazol-5-yl]acetic acid

Mofezolac, a non-steroidal anti-inflammatory drug (NSAID), is a selective, reversible and orally active COX-1 inhibitor with an IC50 of 1·44 nM

ChemicalCAS78967-07-4MW339.34FormulaC19H17NO5
CAS number
78967-07-4
Molecular weight
339.34
Formula
C19H17NO5
Solubility
DMSO : 100 mg/mL (294·69 mM; Need ultrasonic)
InChIKey
DJEIHHYCDCTAAH-UHFFFAOYSA-N
Catalogue number
GC61843
Brand
GLPBIO
Computed properties PubChem CID 4237 · XLogP 3.1 · TPSA 81.8 Ų · H-bond donors 1
XLogP
3.1
TPSA
81.8 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
25

SMILES COC1=CC=C(C=C1)C2=C(ON=C2C3=CC=C(C=C3)OC)CC(=O)O

Computed descriptors from PubChem (CID 4237), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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