Loading...
Chemical structure of RWJ-56110 dihydrochloride

GC61777

RWJ-56110 dihydrochloride

Also known as (2S)-4-amino-N-benzyl-2-[[(2S)-2-[[1-[(2,6-dichlorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)indol-6-yl]carbamoylamino]-3-(3,4-difluorophenyl)propanoyl]amino]butanamide;dihydrochloride

RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0·44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4

ChemicalCAS2387505-58-8MW863.65FormulaC41H45Cl4F2N7O3
CAS number
2387505-58-8
Molecular weight
863.65
Formula
C41H45Cl4F2N7O3
Solubility
DMSO ： 200 mg/mL (231·58 mM; Need ultrasonic)
InChIKey
MGZSVSHDIOPSBO-ZEUUMAKDSA-N
Catalogue number
GC61777
Brand
GLPBIO
Computed properties PubChem CID 90488773 · TPSA 134 Ų · H-bond donors 7 · H-bond acceptors 7
TPSA
134 Ų
H-bond donors
7
H-bond acceptors
7
Rotatable bonds
15
Heavy atoms
57

SMILES C1CCN(C1)CC2=CN(C3=C2C=CC(=C3)NC(=O)N[C@@H](CC4=CC(=C(C=C4)F)F)C(=O)N[C@@H](CCN)C(=O)NCC5=CC=CC=C5)CC6=C(C=CC=C6Cl)Cl.Cl.Cl

Computed descriptors from PubChem (CID 90488773), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.