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Chemical structure of BAY-899

GC61746

BAY-899

Also known as (5S)-N-[2-(4-fluorophenoxy)pyrimidin-5-yl]-5-(4-fluorophenyl)-7,8-dihydro-5H-1,6-naphthyridine-6-carboxamide

BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively

ChemicalCAS2471967-92-5MW459.45FormulaC25H19F2N5O2
CAS number
2471967-92-5
Molecular weight
459.45
Formula
C25H19F2N5O2
InChIKey
VKQBTIMLSDGNLG-QHCPKHFHSA-N
Catalogue number
GC61746
Brand
GLPBIO
Computed properties PubChem CID 139600336 · XLogP 3.6 · TPSA 80.2 Ų · H-bond donors 1
XLogP
3.6
TPSA
80.2 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
34

SMILES C1CN([C@H](C2=C1N=CC=C2)C3=CC=C(C=C3)F)C(=O)NC4=CN=C(N=C4)OC5=CC=C(C=C5)F

Computed descriptors from PubChem (CID 139600336), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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