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Chemical structure of 2′-Deoxy-2′-fluoroadenosine

GC61667

2′-Deoxy-2′-fluoroadenosine

Also known as (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

2′-Deoxy-2′-fluoroadenosine can be used for thesynthesisof 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA· 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E· coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde)· 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E· coli PNP

ChemicalCAS64183-27-3MW269.23FormulaC10H12FN5O3
CAS number
64183-27-3
Molecular weight
269.23
Formula
C10H12FN5O3
InChIKey
ZGYYPTJWJBEXBC-QYYRPYCUSA-N
Catalogue number
GC61667
Brand
GLPBIO
Computed properties PubChem CID 100253 · XLogP 0 · TPSA 119 Ų · H-bond donors 3
XLogP
0
TPSA
119 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
19

SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N

Computed descriptors from PubChem (CID 100253), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.