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Chemical structure of NAE-IN-M22

GC61623

NAE-IN-M22

Also known as 1-benzyl-N-[2-(2,4-dichlorophenyl)ethyl]piperidin-4-amine

NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range· NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells· NAE-IN-M22 also can inhibit tumor growth in vivo

ChemicalCAS864420-54-2MW363.32FormulaC20H24Cl2N2
CAS number
864420-54-2
Molecular weight
363.32
Formula
C20H24Cl2N2
Solubility
DMSO： 250 mg/mL (688·10 mM)
InChIKey
WMEXQHGRMWPOEF-UHFFFAOYSA-N
Catalogue number
GC61623
Brand
GLPBIO
Computed properties PubChem CID 6456370 · XLogP 5.1 · TPSA 15.3 Ų · H-bond donors 1
XLogP
5.1
TPSA
15.3 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
6
Heavy atoms
24

SMILES C1CN(CCC1NCCC2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3

Computed descriptors from PubChem (CID 6456370), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.