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Chemical structure of Truli

GC61527

Truli

Also listed as Lats-IN-1

LATS-IN-1 is an inhibitor of LATS1 and LATS2 (IC50 = 2nM for both)· Lats-IN-1 inhibits core Hippo pathway kinases and activates downstream effector molecules YAP/TAZ, which translocate to the nucleus, driving expression of genes that promote cell proliferation and survival· Lats-IN-1 is primarily used to treat tissue regeneration and degenerative diseases

ChemicalCAS1424635-83-5MW334.39FormulaC18H14N4OS
CAS number
1424635-83-5
Molecular weight
334.39
Formula
C18H14N4OS
Solubility
DMSO： 83·33 mg/mL (249·20 mM)
InChIKey
VTXBMVZVPUSAJF-UHFFFAOYSA-N
Catalogue number
GC61527
Brand
GLPBIO
Computed properties PubChem CID 71890885 · XLogP 3 · TPSA 86.7 Ų · H-bond donors 1
XLogP
3
TPSA
86.7 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
24

SMILES C1=CC=C(C=C1)CN2C=CSC2=NC(=O)C3=CNC4=C3C=CC=N4

Computed descriptors from PubChem (CID 71890885), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.