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Chemical structure of Acolbifene hydrochloride

GC61514

Acolbifene hydrochloride

Also known as (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-2H-chromen-7-ol;hydrochloride

Acolbifene (EM-652) hydrochloride, an active metabolite of EM800, is an orally active, cancer-preventing selective estrogen receptor modulator (SERM)· Acolbifene (EM-652) hydrochloride inhibits estradiol (E2)-induced transcriptional activity of ERα (IC50=2 nM) and ERβ (IC50=0·4 nM)· Acolbifene (EM-652) hydrochloride exerts a potent and pure antiestrogenic action in the mammary gland and uterus· Anticarcinogenic properties

ChemicalCAS252555-01-4MW494.02FormulaC29H32ClNO4
CAS number
252555-01-4
Molecular weight
494.02
Formula
C29H32ClNO4
Solubility
DMSO： 180 mg/mL (364·36 mM)
InChIKey
BYQDPIXWTVEVEA-JMAPEOGHSA-N
Catalogue number
GC61514
Brand
GLPBIO
Computed properties PubChem CID 155436 · TPSA 62.2 Ų · H-bond donors 3 · H-bond acceptors 5
TPSA
62.2 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
35

SMILES CC1=C([C@@H](OC2=C1C=CC(=C2)O)C3=CC=C(C=C3)OCCN4CCCCC4)C5=CC=C(C=C5)O.Cl

Computed descriptors from PubChem (CID 155436), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.