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Chemical structure of Raf inhibitor 2

GC61485

Raf inhibitor 2

Also known as (3Z)-5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1H-indol-2-one

Raf inhibitor 2 is a potent raf kinase (IC50<1·0 μM) inhibitor, compound 32, extracted from patent EP1003721B1· Raf inhibitor 2 can be used for cancer research

ChemicalCAS220904-99-4MW429.49FormulaC15H8Br2ClNO2
CAS number
220904-99-4
Molecular weight
429.49
Formula
C15H8Br2ClNO2
Solubility
DMSO: 100 mg/mL (232·83 mM)
InChIKey
MPIHOJMBMIMKAJ-KMKOMSMNSA-N
Catalogue number
GC61485
Brand
GLPBIO
Computed properties PubChem CID 25014542 · XLogP 4.6 · TPSA 49.3 Ų · H-bond donors 2
XLogP
4.6
TPSA
49.3 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
21

SMILES C1=CC2=C(C=C1Cl)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2

Computed descriptors from PubChem (CID 25014542), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.