Loading...
Chemical structure of GR 125743

GC61464

GR 125743

Also known as N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methyl-4-pyridin-4-ylbenzamide

GR 125743 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8·85 and 8·31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively

ChemicalCAS148547-33-5MW416.52FormulaC25H28N4O2
CAS number
148547-33-5
Molecular weight
416.52
Formula
C25H28N4O2
Solubility
DMSO： 100 mg/mL (240·08 mM)
InChIKey
GNOXPYACARZYMW-UHFFFAOYSA-N
Catalogue number
GC61464
Brand
GLPBIO
Computed properties PubChem CID 5311130 · XLogP 3.6 · TPSA 57.7 Ų · H-bond donors 1
XLogP
3.6
TPSA
57.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
31

SMILES CC1=C(C=CC(=C1)C(=O)NC2=CC(=C(C=C2)OC)N3CCN(CC3)C)C4=CC=NC=C4

Computed descriptors from PubChem (CID 5311130), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.