GC61395
Palbociclib-propargyl
Also known as 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-prop-2-ynylpiperazin-1-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7-one
Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10· CP-10 shows a DC50 of 2·1 nM for CDK6
ChemicalCAS2366269-23-8MW485.58FormulaC27H31N7O2
- CAS number
- 2366269-23-8
- Molecular weight
- 485.58
- Formula
- C27H31N7O2
- InChIKey
- SLFZXPQZLOODKL-UHFFFAOYSA-N
- Catalogue number
- GC61395
- Brand
- GLPBIO
Computed properties PubChem CID 139600348 · XLogP 2.4 · TPSA 94.6 Ų · H-bond donors 1
- XLogP
- 2.4
- TPSA
- 94.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 6
- Heavy atoms
- 36
SMILES CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)CC#C)C5CCCC5)C(=O)C
Computed descriptors from PubChem (CID 139600348), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il