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Chemical structure of ZZW-115 hydrochloride

GC61393

ZZW-115 hydrochloride

Also known as N,N-dimethyl-2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanamine;trihydrochloride

ZZW-115 hydrochloride is a potent NUPR1 inhibitor, with a Kd of 2·1 μM· ZZW-115 hydrochloride induces tumor cell death by necroptosis and apoptosis· Anticancer activity

ChemicalCAS10122-45-9MW573.97FormulaC24H34Cl3F3N4S
CAS number
10122-45-9
Molecular weight
573.97
Formula
C24H34Cl3F3N4S
Solubility
Water: 100 mg/mL (174·23 mM)
InChIKey
OBSKIDNFCBBXKJ-UHFFFAOYSA-N
Catalogue number
GC61393
Brand
GLPBIO
Computed properties PubChem CID 154573789 · TPSA 38.3 Ų · H-bond donors 3 · H-bond acceptors 8
TPSA
38.3 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
35

SMILES CN(C)CCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl.Cl.Cl

Computed descriptors from PubChem (CID 154573789), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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