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Chemical structure of Pralsetinib

GC61346

Pralsetinib

Also listed as trans-Pralsetinib

trans-Pralsetinib (trans-BLU-667) is a rearranged during transfection (RET) inhibitor extracted from patent US20170121312A1, Compound Example 129

ChemicalCAS2097132-93-7MW533.6FormulaC27H32FN9O2
CAS number
2097132-93-7
Molecular weight
533.6
Formula
C27H32FN9O2
InChIKey
GBLBJPZSROAGMF-SIYOEGHHSA-N
Catalogue number
GC61346
Brand
GLPBIO
Computed properties PubChem CID 129073603 · XLogP 3.1 · TPSA 136 Ų · H-bond donors 3
XLogP
3.1
TPSA
136 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
39

SMILES CC1=CC(=NN1)NC2=NC(=NC(=C2)C)C3CCC(CC3)(C(=O)N[C@@H](C)C4=CN=C(C=C4)N5C=C(C=N5)F)OC

Computed descriptors from PubChem (CID 129073603), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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