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Chemical structure of PIP-199

GC61188

PIP-199

Also known as ethyl 4-[(1-hydroxy-2-phenylindol-3-yl)-pyridin-2-ylmethyl]piperazine-1-carboxylate

PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM· PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics

ChemicalCAS622795-76-0MW456.54FormulaC27H28N4O3
CAS number
622795-76-0
Molecular weight
456.54
Formula
C27H28N4O3
InChIKey
ROTCTSYSZSYNHB-UHFFFAOYSA-N
Catalogue number
GC61188
Brand
GLPBIO
Computed properties PubChem CID 4081132 · XLogP 4.3 · TPSA 70.8 Ų · H-bond donors 1
XLogP
4.3
TPSA
70.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
34

SMILES CCOC(=O)N1CCN(CC1)C(C2=CC=CC=N2)C3=C(N(C4=CC=CC=C43)O)C5=CC=CC=C5

Computed descriptors from PubChem (CID 4081132), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.