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Chemical structure of Lenalidomide-C4-NH2 hydrochloride

GC60984

Lenalidomide-C4-NH2 hydrochloride

Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein· Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0·98 nM and 13·7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively

ChemicalMW351.83FormulaC17H22ClN3O3
CAS number
Molecular weight
351.83
Formula
C17H22ClN3O3
Solubility
DMSO: 130 mg/mL (369·50 mM)
Catalogue number
GC60984
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.