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Chemical structure of GOT1 inhibitor-1

GC60884

GOT1 inhibitor-1

Also known as N-(4-chlorophenyl)-4-(1H-indol-4-yl)piperazine-1-carboxamide

GOT1 inhibitor-1 is a small-molecule selective inhibitor of GOT1 (glutamic oxaloacetic transaminase 1) with an IC50 of 8·2 μM· GOT1 inhibitor-1 has potential application value in cancer therapy

ChemicalCAS732973-87-4MW354.83FormulaC19H19ClN4O
CAS number
732973-87-4
Molecular weight
354.83
Formula
C19H19ClN4O
Solubility
DMSO: 125 mg/mL (352·28 mM); Water: < 0·1 mg/mL (insoluble)
InChIKey
VVVZKBOSNCHQEJ-UHFFFAOYSA-N
Catalogue number
GC60884
Brand
GLPBIO
Computed properties PubChem CID 2802665 · XLogP 3.5 · TPSA 51.4 Ų · H-bond donors 2
XLogP
3.5
TPSA
51.4 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
25

SMILES C1CN(CCN1C2=CC=CC3=C2C=CN3)C(=O)NC4=CC=C(C=C4)Cl

Computed descriptors from PubChem (CID 2802665), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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