GC60863
GAK inhibitor 49
Also known as 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0·54 nM and a cell IC50 of 56 nM
ChemicalCAS319492-82-5MW370.4FormulaC20H22N2O5
- CAS number
- 319492-82-5
- Molecular weight
- 370.4
- Formula
- C20H22N2O5
- Solubility
- DMSO： 50 mg/mL (134·99 mM; ultrasonic and warming and heat to 80°C)
- InChIKey
- VYPGLYMWNDRFGZ-UHFFFAOYSA-N
- Catalogue number
- GC60863
- Brand
- GLPBIO
Computed properties PubChem CID 5330475 · XLogP 3.6 · TPSA 71.1 Ų · H-bond donors 1
- XLogP
- 3.6
- TPSA
- 71.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 7
- Heavy atoms
- 27
SMILES COC1=CC(=CC(=C1OC)OC)NC2=C3C=C(C(=CC3=NC=C2)OC)OC
Computed descriptors from PubChem (CID 5330475), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il