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Chemical structure of Fmoc-NH-PEG4-CH2COOH

GC60853

Fmoc-NH-PEG4-CH2COOH

Also known as 2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· Fmoc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS437655-95-3MW473.52FormulaC25H31NO8
CAS number
437655-95-3
Molecular weight
473.52
Formula
C25H31NO8
InChIKey
XPNLDOFYRFOXLR-UHFFFAOYSA-N
Catalogue number
GC60853
Brand
GLPBIO
Computed properties PubChem CID 66615355 · XLogP 2.1 · TPSA 113 Ų · H-bond donors 2
XLogP
2.1
TPSA
113 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
17
Heavy atoms
34

SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCC(=O)O

Computed descriptors from PubChem (CID 66615355), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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