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Chemical structure of Fmoc-NH-PEG1-CH2COOH

GC60851

Fmoc-NH-PEG1-CH2COOH

Also known as 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]acetic acid

Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS260367-12-2MW341.36FormulaC19H19NO5
CAS number
260367-12-2
Molecular weight
341.36
Formula
C19H19NO5
InChIKey
LBVXPUINIMIGAU-UHFFFAOYSA-N
Catalogue number
GC60851
Brand
GLPBIO
Computed properties PubChem CID 45599183 · XLogP 2.5 · TPSA 84.9 Ų · H-bond donors 2
XLogP
2.5
TPSA
84.9 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
25

SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCC(=O)O

Computed descriptors from PubChem (CID 45599183), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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