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Chemical structure of FB23

GC60833

FB23

Also known as 2-[2,6-dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]benzoic acid

FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM· FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity

ChemicalCAS2243736-35-6MW377.22FormulaC18H14Cl2N2O3
CAS number
2243736-35-6
Molecular weight
377.22
Formula
C18H14Cl2N2O3
Solubility
DMSO： 125 mg/mL (331·37 mM)
InChIKey
VUXZATVQMFSUCM-UHFFFAOYSA-N
Catalogue number
GC60833
Brand
GLPBIO
Computed properties PubChem CID 138393314 · XLogP 5.7 · TPSA 75.4 Ų · H-bond donors 2
XLogP
5.7
TPSA
75.4 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
25

SMILES CC1=C(C(=NO1)C)C2=CC(=C(C(=C2)Cl)NC3=CC=CC=C3C(=O)O)Cl

Computed descriptors from PubChem (CID 138393314), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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