Loading...
Chemical structure of Chk1-IN-5

GC60698

Chk1-IN-5

Also known as 5-[[5-[2-(3-aminopropoxy)-4-fluoro-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile

Chk1-IN-5 is a potent checkpoint kinase 1 (Chk1) inhibitor· Chk1-IN-5 inhibits Chk1 phosphorylation and inhibits tumor growth in colon cancer xenograft model

ChemicalCAS2120398-39-0MW383.38FormulaC18H18FN7O2
CAS number
2120398-39-0
Molecular weight
383.38
Formula
C18H18FN7O2
InChIKey
CAAWSPMLCMFRMK-UHFFFAOYSA-N
Catalogue number
GC60698
Brand
GLPBIO
Computed properties PubChem CID 130299459 · XLogP 1.5 · TPSA 135 Ų · H-bond donors 3
XLogP
1.5
TPSA
135 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
28

SMILES COC1=C(C(=CC(=C1)F)OCCCN)C2=CC(=NN2)NC3=NC=C(N=C3)C#N

Computed descriptors from PubChem (CID 130299459), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.