GC60625
BC-DXI-843
Also known as (2S)-3-(1H-indol-3-yl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-[(4-methylphenyl)sulfonylamino]propanamide
BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with an IC50 of 0·92 μM, more than 100-fold selectivity over AIMP2 (IC50 >100 μM) in a luciferase assay· BC-DXI-843 acts as a promising lead targeting AIMP2-DX2 in lung cancer
ChemicalCAS2421117-98-6MW546.66FormulaC28H26N4O4S2
- CAS number
- 2421117-98-6
- Molecular weight
- 546.66
- Formula
- C28H26N4O4S2
- Solubility
- DMSO： 250 mg/mL (457·32 mM)
- InChIKey
- VLPGAOXBMXGNGM-VWLOTQADSA-N
- Catalogue number
- GC60625
- Brand
- GLPBIO
Computed properties PubChem CID 146673132 · XLogP 5.3 · TPSA 150 Ų · H-bond donors 3
- XLogP
- 5.3
- TPSA
- 150 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 9
- Heavy atoms
- 38
SMILES CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NC4=NC(=CS4)C5=CC=C(C=C5)OC
Computed descriptors from PubChem (CID 146673132), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il