Loading...
Chemical structure of SHP836

GC60337

SHP836

Also known as 5-(2,3-dichlorophenyl)-2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]pyrimidin-4-amine

SHP836 is a SHP2 allosteric inhibitor, with an IC50 of 12 μM for the full length SHP2

ChemicalCAS1957276-35-5MW352.26FormulaC16H19Cl2N5
CAS number
1957276-35-5
Molecular weight
352.26
Formula
C16H19Cl2N5
Solubility
DMSO： 250 mg/mL (709·70 mM)
InChIKey
SKFRRNOLFFQBQU-AOOOYVTPSA-N
Catalogue number
GC60337
Brand
GLPBIO
Computed properties PubChem CID 76966642 · XLogP 3.4 · TPSA 67.1 Ų · H-bond donors 2
XLogP
3.4
TPSA
67.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
23

SMILES C[C@@H]1CN(C[C@@H](N1)C)C2=NC=C(C(=N2)N)C3=C(C(=CC=C3)Cl)Cl

Computed descriptors from PubChem (CID 76966642), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.