Loading...
Chemical structure of PF-03463275

GC60284

PF-03463275

Also known as N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-[[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]imidazole-4-carboxamide

PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11·6 nM

ChemicalCAS1173239-39-8MW376.86FormulaC19H22ClFN4O
CAS number
1173239-39-8
Molecular weight
376.86
Formula
C19H22ClFN4O
Solubility
DMSO： 33·33 mg/mL (88·44 mM)
InChIKey
KYLOBHXXQOZRKK-YIONKMFJSA-N
Catalogue number
GC60284
Brand
GLPBIO
Computed properties PubChem CID 44156901 · XLogP 2.4 · TPSA 41.4 Ų · H-bond donors 0
XLogP
2.4
TPSA
41.4 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
26

SMILES CN1C[C@@H]2[C@H](C1)C2CN(CC3=CC(=C(C=C3)F)Cl)C(=O)C4=CN(C=N4)C

Computed descriptors from PubChem (CID 44156901), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.