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Chemical structure of Pentagamavunon-1

GC60283

Pentagamavunon-1

Also known as (2E,5E)-2,5-bis[(4-hydroxy-3,5-dimethylphenyl)methylidene]cyclopentan-1-one

Pentagamavunon-1 (PGV-1), a Curcumin analog with oral activity, targets on several molecular mechanisms to induce apoptosis including inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF)· PGV-1 inhibits NF-κB activation

ChemicalCAS27060-70-4MW348.43FormulaC23H24O3
CAS number
27060-70-4
Molecular weight
348.43
Formula
C23H24O3
Solubility
DMSO: 50 mg/mL (143·50 mM)
InChIKey
OHSKJRMWVIVJCP-AYKLPDECSA-N
Catalogue number
GC60283
Brand
GLPBIO
Computed properties PubChem CID 10760152 · XLogP 5.3 · TPSA 57.5 Ų · H-bond donors 2
XLogP
5.3
TPSA
57.5 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
2
Heavy atoms
26

SMILES CC1=CC(=CC(=C1O)C)/C=C\2/C(=O)/C(=C/C3=CC(=C(C(=C3)C)O)C)/CC2

Computed descriptors from PubChem (CID 10760152), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.