Loading...
Chemical structure of KGA-2727

GC60217

KGA-2727

Also known as 3-[3-[3-methyl-4-[[5-propan-2-yl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-pyrazol-4-yl]methyl]phenoxy]propylamino]propanamide

KGA-2727 is a first selective, high-affinity and orally active SGLT1 inhibitor with Kis of 97·4 nM and 43·5 nM for human and rat SGLT1, respectively

ChemicalCAS666842-36-0MW536.62FormulaC26H40N4O8
CAS number
666842-36-0
Molecular weight
536.62
Formula
C26H40N4O8
Solubility
DMSO： 100 mg/mL (186·35 mM)
InChIKey
MDBARDSTXONTFS-MNDUUMEHSA-N
Catalogue number
GC60217
Brand
GLPBIO
Computed properties PubChem CID 10052896 · XLogP 0.6 · TPSA 192 Ų · H-bond donors 7
XLogP
0.6
TPSA
192 Ų
H-bond donors
7
H-bond acceptors
10
Rotatable bonds
14
Heavy atoms
38

SMILES CC1=C(C=CC(=C1)OCCCNCCC(=O)N)CC2=C(NN=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(C)C

Computed descriptors from PubChem (CID 10052896), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.