Loading...
Chemical structure of Fedratinib Hydrochloride

GC60161

Fedratinib Hydrochloride

Also listed as Fedratinib hydrochloride hydrate

Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase· Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively· Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research

ChemicalCAS1374744-69-0MW615.62FormulaC27H40Cl2N6O4S
CAS number
1374744-69-0
Molecular weight
615.62
Formula
C27H40Cl2N6O4S
Solubility
DMSO： 250 mg/mL (406·09 mM)
InChIKey
QAFZLTVOFJHYDF-UHFFFAOYSA-N
Catalogue number
GC60161
Brand
GLPBIO
Computed properties PubChem CID 67517580 · TPSA 118 Ų · H-bond donors 6 · H-bond acceptors 10
TPSA
118 Ų
H-bond donors
6
H-bond acceptors
10
Rotatable bonds
11
Heavy atoms
40

SMILES CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4.O.Cl.Cl

Computed descriptors from PubChem (CID 67517580), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.