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Chemical structure of Cyclo(-RGDfK) TFA

GC60117

Cyclo(-RGDfK) TFA

Also known as 2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid;2,2,2-trifluoroacetic acid

Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0·94 nM· Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface

ChemicalCAS500577-51-5MW717.69FormulaC29H42F3N9O9
CAS number
500577-51-5
Molecular weight
717.69
Formula
C29H42F3N9O9
Solubility
DMSO： 100 mg/mL (139·34 mM); Water： 33·33 mg/mL (46·44 mM)
InChIKey
WHCQIPJAWCYHFT-HXSCNMCGSA-N
Catalogue number
GC60117
Brand
GLPBIO
Computed properties PubChem CID 91759592 · TPSA 311 Ų · H-bond donors 10 · H-bond acceptors 14
TPSA
311 Ų
H-bond donors
10
H-bond acceptors
14
Rotatable bonds
12
Heavy atoms
50

SMILES C1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 91759592), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.