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Chemical structure of Clitocine

GC60111

Clitocine

Also known as (2R,3R,4S,5R)-2-[(6-amino-5-nitropyrimidin-4-yl)amino]-5-(hydroxymethyl)oxolane-3,4-diol

Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent· Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles· Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1· Anticancer activity

ChemicalCAS105798-74-1MW287.23FormulaC9H13N5O6
CAS number
105798-74-1
Molecular weight
287.23
Formula
C9H13N5O6
InChIKey
OHEMBWZZEKCBAS-UUOKFMHZSA-N
Catalogue number
GC60111
Brand
GLPBIO
Computed properties PubChem CID 129111 · XLogP -0.4 · TPSA 180 Ų · H-bond donors 5
XLogP
-0.4
TPSA
180 Ų
H-bond donors
5
H-bond acceptors
10
Rotatable bonds
3
Heavy atoms
20

SMILES C1=NC(=C(C(=N1)N[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)[N+](=O)[O-])N

Computed descriptors from PubChem (CID 129111), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.