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Chemical structure of (R)-DNMDP

GC60002

(R)-DNMDP

Also known as (4R)-3-[4-(diethylamino)-3-nitrophenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one

(R)-DNMDP is a potent and selective cancer cell cytotoxic agent· (R)-DNMDP, the R-form of DNMDP, binds PDE3A directly· (R)-DNMDP has a 500-fold lower EC50 compared to the (S)-enantiomer in HeLa cell line

ChemicalCAS1630760-60-9MW304.34FormulaC15H20N4O3
CAS number
1630760-60-9
Molecular weight
304.34
Formula
C15H20N4O3
InChIKey
YOSSKNZHADPXJX-SNVBAGLBSA-N
Catalogue number
GC60002
Brand
GLPBIO
Computed properties PubChem CID 7122097 · XLogP 2.2 · TPSA 90.5 Ų · H-bond donors 1
XLogP
2.2
TPSA
90.5 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
22

SMILES CCN(CC)C1=C(C=C(C=C1)C2=NNC(=O)C[C@H]2C)[N+](=O)[O-]

Computed descriptors from PubChem (CID 7122097), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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