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Chemical structure of HEMTAC 26

GC59458

HEMTAC 26

Also known as 2-[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]piperazin-1-yl]-N-[[1-[4-[2-amino-4-chloro-7-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]but-3-ynyl]triazol-4-yl]methyl]acetamide

CDK6 and CDK4 HSP90-mediated targeting chimera (HEMTAC) Degrader

ChemicalCAS2821803-61-4MW953.51FormulaC48H53ClN16O4
CAS number
2821803-61-4
Molecular weight
953.51
Formula
C48H53ClN16O4
Solubility
DMSO： 95·35mg/mL
InChIKey
VSAXVERDPZMCPX-UHFFFAOYSA-N
Catalogue number
GC59458
Brand
GLPBIO
Computed properties PubChem CID 167312304 · XLogP 3.8 · TPSA 233 Ų · H-bond donors 3
XLogP
3.8
TPSA
233 Ų
H-bond donors
3
H-bond acceptors
16
Rotatable bonds
15
Heavy atoms
69

SMILES CC1=CN=C(C(=C1OC)C)CN2C=C(C3=C2N=C(N=C3Cl)N)C#CCCN4C=C(N=N4)CNC(=O)CN5CCN(CC5)C6=CN=C(C=C6)NC7=NC=C8C(=C(C(=O)N(C8=N7)C9CCCC9)C(=O)C)C

Computed descriptors from PubChem (CID 167312304), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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