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Chemical structure of Pomalidomide 4'-PEG5-acid

GC50713

Pomalidomide 4'-PEG5-acid

Also known as 3-[2-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology

ChemicalCAS2139348-63-1MW565.58FormulaC26H35N3O11
CAS number
2139348-63-1
Molecular weight
565.58
Formula
C26H35N3O11
InChIKey
PMCQLKMOQUEEDR-UHFFFAOYSA-N
Catalogue number
GC50713
Brand
GLPBIO
Computed properties PubChem CID 132020460 · XLogP -0.4 · TPSA 179 Ų · H-bond donors 3
XLogP
-0.4
TPSA
179 Ų
H-bond donors
3
H-bond acceptors
12
Rotatable bonds
20
Heavy atoms
40

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCOCCC(=O)O

Computed descriptors from PubChem (CID 132020460), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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