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Chemical structure of Thalidomide 4'-oxyacetamide-alkylC2-amine

GC50620

Thalidomide 4'-oxyacetamide-alkylC2-amine

Also known as N-(2-aminoethyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;hydrochloride

Thalidomide 4'-oxyacetamide-alkylC2-amine incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker· Thalidomide 4'-oxyacetamide-alkylC2-amine can be used to design the PROTACs

ChemicalCAS2341841-02-7MW410.81FormulaC17H18N4O6·HCl
CAS number
2341841-02-7
Molecular weight
410.81
Formula
C17H18N4O6·HCl
Solubility
Soluble in DMSO
InChIKey
CVVNNSLQIHNBSU-UHFFFAOYSA-N
Catalogue number
GC50620
Brand
GLPBIO
Computed properties PubChem CID 138991800 · TPSA 148 Ų · H-bond donors 4 · H-bond acceptors 7
TPSA
148 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
28

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)NCCN.Cl

Computed descriptors from PubChem (CID 138991800), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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