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Chemical structure of VU 0424465

GC50598

VU 0424465

Also known as 5-[2-(3-fluorophenyl)ethynyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]pyridine-2-carboxamide

Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity

ChemicalCAS1428630-85-6MW326.37FormulaC19H19FN2O2
CAS number
1428630-85-6
Molecular weight
326.37
Formula
C19H19FN2O2
Solubility
Soluble in DMSO
InChIKey
ZPKZAFDYFVJULO-CYBMUJFWSA-N
Catalogue number
GC50598
Brand
GLPBIO
Computed properties PubChem CID 53384864 · XLogP 2.9 · TPSA 62.2 Ų · H-bond donors 2
XLogP
2.9
TPSA
62.2 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
24

SMILES C[C@H](C(C)(C)O)NC(=O)C1=NC=C(C=C1)C#CC2=CC(=CC=C2)F

Computed descriptors from PubChem (CID 53384864), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.