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Chemical structure of YNT 185

GC50559

YNT 185

Also known as 2-(dimethylamino)-N-[2-[3-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]anilino]ethyl]benzamide;dihydrochloride

YNT 185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC50s of 0·028 and 2·75 μM for OX2R and OX1R, respectively

ChemicalCAS1804978-82-2MW688.66FormulaC33H37N5O52HCl
CAS number
1804978-82-2
Molecular weight
688.66
Formula
C33H37N5O52HCl
Solubility
DMSO: 68·87mg/ml;water: 68·87mg/ml
InChIKey
AIORBDHFHVKRIY-UHFFFAOYSA-N
Catalogue number
GC50559
Brand
GLPBIO
Computed properties PubChem CID 140307520 · TPSA 128 Ų · H-bond donors 5 · H-bond acceptors 8
TPSA
128 Ų
H-bond donors
5
H-bond acceptors
8
Rotatable bonds
12
Heavy atoms
46

SMILES CN(C)C1=CC=CC=C1C(=O)NCCNC2=CC(=CC=C2)NS(=O)(=O)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(=O)N(C)C)OC.Cl.Cl

Computed descriptors from PubChem (CID 140307520), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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